Jefferies Initiates Buy Rating on Rocket Pharmaceuticals, Citing Promising Gene Therapies

Jefferies Initiates Buy Rating on Rocket Pharmaceuticals, Citing Promising Gene Therapies

Jefferies has initiated coverage of Rocket Pharmaceuticals (RCKT) with a “buy” rating and a $29 price target, driven by optimism surrounding the company’s experimental gene therapies. This positive outlook sent RCKT shares up 5.5% intraday Wednesday.

Jefferies analysts highlighted Rocket Pharma’s pipeline of five or more gene therapy treatments for rare diseases. A key focus of their analysis is RP-A501 (AAV9), a treatment for Danon heart disease, a rare genetic condition with no current treatment options. This experimental therapy, according to Jefferies, has a high probability of success (65-75%) in its pivotal Phase II study next year. The analysts project that RP-A501 could represent a $1 billion market opportunity for Rocket Pharmaceuticals. Furthermore, a successful trial outcome could potentially double the company’s stock price, offering a favorable risk/reward profile at a $1.3 billion market capitalization.

The analysts’ $29 price target is based on a discounted cash flow (DCF) sum-of-the-parts (SOTP) valuation. This positive assessment provides a much-needed boost for Rocket Pharmaceuticals investors, who have seen the stock steadily decline this year, reaching a more than two-year low last week. Despite Wednesday’s gains, RCKT remains down nearly 60% year-to-date in 2024.

This positive outlook from Jefferies underscores the potential of Rocket Pharmaceuticals’ gene therapy pipeline, particularly RP-A501 for Danon heart disease. The upcoming Phase II trial results will be a critical catalyst for the company’s future prospects.

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